hrp0086p1-p476 | Fat Metabolism and Obesity P1 | ESPE2016

Polysomnography in Obese Children with and without Prader-Willi

Bogova Elena , Volevodz Natalya , Peterkova Valentina , Poluektov Mikhail

Background: Several studies found a high prevalence of sleep disorders in PWS patients. It is assumed that Prader-Willi Syndrome (PWS) patients are at a high risk of sleep disordered breathing, such as obstructive sleep apnea (OSA), because of their childhood obesity, associated with muscle hypotonia, leading to upper airway collapse.Objective and hypotheses: We studied a group of PWS children (genetically confirmed, non-GH-treated) who performed complet...